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A:
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Incidence of nausea and vomiting in postoperative day 1 after pediatric cardiac surgery: incidence and correlation with opioid use.
The objectives of this study were to measure the incidence of postoperative nausea and vomiting (PONV) on postoperative day 1 (POD 1) after pediatric cardiac surgery and to determine whether the use of opioids (PO) is correlated with PONV on POD 1. This was a retrospective cohort study in which patients were grouped based on PO use in the POD 1 anesthesia. Patients were excluded if they were younger than one year, had extracorporeal circulation, had a high-risk PONV score on POD 0, had incomplete medical records, or if they were not on PO therapy on POD 0. A total of 97 patients were included for analysis, of whom 67 were nonopioid and 30 were opioid group. The incidence of PONV on POD 1 was 24.6%. The incidence of PONV was statistically significantly higher in the opioid group (P =.003). Patients in the opioid group had a longer PACU time (9.8 vs 4.9 hours, P =.03), but no difference in time to extubation or discharge. The use of opioids was correlated with an increased incidence of PONV on POD 1 (P =.03) and in general was not associated with increased morbidity. The use of opioids on POD 0 may be associated with a higher incidence of PONV on be359ba680
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